This page lists the head-to-head record of Siena vs Roma including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Roma | Siena | Draws |
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| Total Matches | 20 | 12 | 6 | 2 |
| At Stadio Olimpico | 10 | 6 | 3 | 1 |
| At Montepaschi Arena | 10 | 6 | 3 | 1 |
| Cup Matches | 2 | 1 | 1 | 0 |
| Serie A Matches | 18 | 11 | 5 | 2 |
| Total Goals Scored | 58 | 40 | 18 | |
Last 50 Roma vs Siena Matches
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| 2013 28 April | | Serie A | Roma | 4 - 0 | Robur Siena |
| 2012 2 December | | Serie A | Robur Siena | 1 - 3 | Roma |
| 2012 13 February | | Serie A | Robur Siena | 1 - 0 | Roma |
| 2011 22 September | | Serie A | Roma | 1 - 1 | Robur Siena |
| 2010 31 January | | Serie A | Roma | 2 - 1 | Robur Siena |
| 2009 13 September | | Serie A | Robur Siena | 1 - 2 | Roma |
| 2009 21 February | | Serie A | Roma | 1 - 0 | Robur Siena |
| 2008 5 October | | Serie A | Robur Siena | 1 - 0 | Roma |
| 2008 3 February | | Serie A | Robur Siena | 3 - 0 | Roma |
| 2007 2 September | | Serie A | Roma | 3 - 0 | Robur Siena |
| 2007 28 January | | Serie A | Roma | 1 - 0 | Robur Siena |
| 2006 16 September | | Serie A | Robur Siena | 1 - 3 | Roma |
| 2006 11 February | | Serie A | Robur Siena | 0 - 2 | Roma |
| 2005 1 October | | Serie A | Roma | 2 - 3 | Robur Siena |
| 2005 19 April | | Serie A | Roma | 0 - 2 | Robur Siena |
| 2005 12 January | | Cup | Robur Siena | 1 - 5 | Roma |
| 2004 26 November | | Serie A | Robur Siena | 0 - 4 | Roma |
| 2004 18 November | | Cup | Roma | 1 - 2 | Robur Siena |
| 2004 21 February | | Serie A | Roma | 6 - 0 | Robur Siena |
| 2003 4 October | | Serie A | Robur Siena | 0 - 0 | Roma |
Biggest Roma Victory vs Siena
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| 2004 21 February | | Serie A | Roma | 6 - 0 | Robur Siena |
Biggest Siena Victory vs Roma
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| 2008 3 February | | Serie A | Robur Siena | 3 - 0 | Roma |
Biggest Roma Defeat vs Siena
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| 2008 3 February | | Serie A | Robur Siena | 3 - 0 | Roma |
Biggest Siena Defeat vs Roma
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| 2004 21 February | | Serie A | Roma | 6 - 0 | Robur Siena |
Last 5 Roma Home Matches
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| 2024 2 May | | UEFA Europa League | Roma | 0 - 2 | Bayer Leverkusen |
| 2024 22 April | | Serie A | Roma | 1 - 3 | Bologna |
| 2024 18 April | | UEFA Europa League | Roma | 2 - 1 | Milan |
| 2024 6 April | | Serie A | Roma | 1 - 0 | Lazio |
| 2024 17 March | | Serie A | Roma | 1 - 0 | Sassuolo |
Last 5 Siena Home Matches
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| 2023 23 April | | Serie C1 - A | Robur Siena | 1 - 2 | Virtus Entella |
| 2023 6 April | | Serie C1 - A | Robur Siena | 2 - 2 | Gubbio |
| 2023 18 March | | Serie C1 - A | Robur Siena | 0 - 0 | Alessandria |
| 2023 11 March | | Serie C1 - A | Robur Siena | 4 - 0 | Vis Pesaro |
| 2023 25 February | | Serie C1 - A | Robur Siena | 1 - 1 | Recanatese |
Last 5 Roma Away Matches
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| 2024 28 April | | Serie A | Napoli | 2 - 2 | Roma |
| 2024 25 April | | Serie A | Udinese | 1 - 2 | Roma |
| 2024 11 April | | UEFA Europa League | Milan | 0 - 1 | Roma |
| 2024 1 April | | Serie A | Lecce | 0 - 0 | Roma |
| 2024 14 March | | UEFA Europa League | Brighton & Hove Albion | 1 - 0 | Roma |
Last 5 Siena Away Matches
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| 2023 15 April | | Serie C1 - A | Fiorenzuola | 1 - 1 | Robur Siena |
| 2023 1 April | | Serie C1 - A | Fermana | 3 - 1 | Robur Siena |
| 2023 26 March | | Serie C1 - A | Carrarese | 3 - 0 | Robur Siena |
| 2023 14 March | | Serie C1 - A | Lucchese | 1 - 1 | Robur Siena |
| 2023 5 March | | Serie C1 - A | San Donato Tavarnelle | 1 - 1 | Robur Siena |